Human and animal bites

Document Type : Reviewers

Authors

1 Infectious Diseases and Tropical Medicine Research Centre (IDTMRC), Department of Aerospace and Subaquatic Medicine, AJA University of Medical Sciences, Tehran, Iran

2 Department of Emergency Medicine, Besat Hospital, AJA University of Medical Sciences, Tehran, Iran

3 Infectious Diseases and Tropical Medicine Research Centre (IDTMRC), AJA University of Medical Sciences, Tehran, Iran

10.22124/cjes.2023.6539

Abstract

Humans and animal bites are a significant public health problem, with the majority of bites coming from dogs, cats and humans. According to the Centres for Disease Control and Prevention (CDC) data, 250,000 human bites, 400,000 cat bites, and 4.7 million dog bites occur each year in the United States in adults and children, and 20% of these victims require medical care for injuries sustained. The estimated healthcare cost associated with management of cat and dog bites in the United States is > $ 850 million annually and does not take into account the costs to the patient in terms of time off work, rehabilitation, and permanent impairment. Infection is the most common bite-associated complication. The relative risk is determined by the species of the inflicting animal, bite location, host factors, and local wound care. Most infections bring about by mammalian bites are poly-microbial, with mixed aerobic and anaerobic species. The clinical presentation and appropriate treatment of the infected bite wounds vary according to the causative organisms. Human bite wounds have long had a bad reputation for severe infection and frequent complication. This article reviews the dog, cat and human bite. The content of this article provide a comprehensive overview of the types of bites, epidemiology, risk factors, microbiology, as well as using clinical guidelines and treatment through antibiotic therapy.

Keywords


Abrahamian, FM & Goldstein, EJ 2011, Microbiology of animal bite wound infections. Clinical Microbiology Reviews, 24: 231-246.
Abu-Zidan, FM, Hefny, AF, Eid, HO, Bashir, MO & Branicki, FJ 2012, Camel-related injuries: Prospective study of 212 patients. World Journal of Surgery, 36: 2384-2389.
Abubaker, AO 2003, Management of posttraumatic soft tissue infections. Oral and Maxillofacial Surgery Clinics 15: 139-146.
Ambro, BT, Wright, RJ & Heffelfinger, RN 2010, Management of bite woundsin the head and neck. Facial Plastic Surgery, 26: 456-463.
Aziz, H, Rhee, P, Pandit, V, Tang, A, Gries, L & Joseph, B 2015, The current concepts in management of animal (dog, cat, snake, scorpion) and human bite wounds. Journal of Trauma and Acute Care Surgery, 78: 641-648.
Broder, J, Jerrard, D, Olshaker, J & Witting, M 2004, Low risk of infection in selected human bites treated without antibiotics. The American Journal of Emergency Medicine, 22: 10-13.
Brook, I 2009, Management of human and animal bite wound infection: an overview. Current Infectious Disease Reports, 11: 389-395.
Bula-Rudas, FJ & Olcott, JL 2018, Human and animal bites. Pediatrics Review, 39: 490-500, DOI: 10.1542/pir.2017-0212.
Callahan, MV 2019, Bites, stings, and envenoming injuries, Travel Medicine, Elsevier, pp. 437-447.
Chhabra, S, Chhabra, N & Gaba, S 2015, Maxillofacial injuries due to animal bites. Journal of Maxillofacial and Oral Surgery, 14: 142-153.
Darvishi, M, Shokati, B & Karimi, E 2017, Necessary care when facing patients with suspected rabies in emergency department. Iranian Journal of Emergency Medicine, 4: 44-45.
Dhand, NK, Gyeltshen, T, Firestone, S, Zangmo, C, Dema, C, Gyeltshen, R & Ward, MP 2011, Dog bites in humans and estimating human rabies mortality in rabies endemic areas of Bhutan. PLoSNeglected Tropical Diseases, 5: e1391.
Dhillon, J, Hoopes, J & Epp, T 2019, Scoping decades of dog evidence: A scoping review of dog bite-related sequelae. Canadian Journal of Public Health, 1-12.
Dwyer, J, Douglas, T & Van As, A 2007, Dog bite injuries in children: A review of data from a South African paediatric trauma unit. South African Medical Journal, 97: 597-600.
Emet, M, Beyhun, NE, Kosan, Z, Aslan, S, Uzkeser, M & Cakir, ZG 2009, Animal-related injuries: epidemiological and meteorogical features. Annals of Agricultural and Environmental Medicine, 16: 87-92.
Engelbrecht, A 2012, Management of common animal bites in the emergency centre: the most common animal bites to present in emergencies are dog and snake bites. Continuing Medical Education, 30: 401-406.
Enzler, MJ, Berbari, E & Osmon, DR 2011, Antimicrobial prophylaxis in adults, Mayo Clinic Proceedings. Elsevier, pp. 686-701.
Eslamifar, A, Ramezani, A, Razaghi, AM, Falahian, V, Mashayekhi, P, Hazrati, M, Askari, T, Fayaz, A, Aghakhani, A 2008, Arch Iran Med,11:200-2.
Essig Jr, GF, Sheehan, C, Rikhi, S, Elmaraghy, CA & Christophel, JJ 2019, Dog bite injuries to the face: Is there risk with breed ownership? A systematic review with meta-analysis. International Journal of Pediatric Otorhinolaryngology, 117: 182-188.
Gelvez, M, Enrique, R, Gajos, G, Bladimir, J, Carvajal, D & Luis, A 2017, Animal and human bite injuries: a 5-year retrospective study in a large urban public hospital in Venezuela. Oral and Maxillofacial Ssurgery, 21: 425-428.
Ghezta, NK, Bhardwaj, Y, Ram, R, Ahsan, R & Arya, S 2019, Incidence Pattern of Bear-Inflicted Injuries to the Maxillofacial Region—Soft and Hard Tissue Injuries, Their Management, and Sequelae. Journal of Oral and Maxillofacial Surgery 77: 1043. e1041-1043. e1015.
Griego, RD, Rosen, T, Orengo, IF & Wolf, JE 1995, Dog, cat, and human bites: a review. Journal of the American Academy of Dermatology 33: 1019-1029.
Harper, CM, Dowlatshahi, AS & Rozental, TD 2019, Challenging dogma: Optimal treatment of the “Fight Bite”. HAND, 1558944719831238.
Henton, J & Jain, A 2012, Cochrane corner: antibiotic prophylaxis for mammalian bites (Intervention review). Journal of Hand Surgery 37: 804-806.
Hloch, O, Mokra, D, Masopust, J, Hasa, J & Charvat, J 2014, Antibiotic treatment following a dog bite in an immunocompromized patient in order to prevent Capnocytophaga canimorsus infection: A case report. BMC Research Notes, 7: 1-4.
Hui, AY, Hung, LC, Pete, C, Leung, W-K, Chan, PK & Chan, HL 2005, Transmission of hepatitis B by human bite-confirmation by detection of virus in saliva and full genome sequencing. Journal of Clinical Virology 33, 254-256.
Jackson, AC 2016, Human rabies: A 2016 update. Current Infectious Disease Reports 18: 38.
Jenkins, GW, Isaac, R & Mustafa, S, 2018, Human bite injuries to the head and neck: current trends and management protocols in England and Wales. Oral and Maxillofacial Surgery, 22: 77-81.
Kennedy, SA, Stoll, LE & Lauder, AS 2015, Human and other mammalian bite injuries of the hand: Evaluation and management. JAAOS-Journal of the American Academy of Orthopaedic Surgeons, 23: 47-57.
Kern, ZT, Swartley, OM, Neupane, P, Balakrishnan, N, Breitschwerdt, EB, 2019 Pasteurella canis infective endocarditis in a dog. Veterinary Microbiology, 229: 14-19.
Khoobdel M, Akbari M, Aivazi AA, Moosa-Kazemi SH, Yousefi H, Akbari MR, Keshavarzi D, Moradi M 2020, An investigation on permethrin-treated military uniforms against diurnal mosquitoes under field conditions. Advancements in Life Science, 7: 247-251.
Khoobdel M, Akbari M, Aivazi AA, Moosa-Kazemi SH, Yousefi H, Akbari MR, Davood K & Moradi M 2020, An investigation on permethrin-treated military uniforms against diurnal mosquitoes under field conditions. Advancements in Life Sciences 7: 106-109.
Kwoba, EN, Kitala, P, Ochieng, L, Otiang, E, Ndung’u, R, Wambura, G, Hampson, K & Thumbi, S 2019, Dog health and demographic surveillance survey in Western Kenya: Demography and management practices relevant for rabies transmission and control. AAS Open Research, 2: 5.
Langley, RL 2009, Deaths from reptile bites in the United States, 1979-2004. Clinical Toxicology, 47: 44-47.
Lohiya, G-S, Tan-Figueroa, L, Lohiya, S & Lohiya, S 2013, Human bites: bloodborne pathogen risk and postexposure follow-up algorithm. Journal of the National Medical Association, 105: 92-95.
Manning, SE, Rupprecht, CE, Fishbein, D, Hanlon, CA, Lumlertdacha, B, Guerra, M, Meltzer, MI, Dhankhar, P, Vaidya, SA & Jenkins, SR 2008, Human rabies prevention - United States, 2008: Recommendations of the advisory committee on immunization practices. MMWR Recommendations and Reports, 57: 1-28.
Merriam, C, Fernandez, H, Citron, D, Tyrrell, K, Warren, Y, Goldstein, E 2003 Bacteriology of Human Bite Wound Infections, 9: 83-86.
Moran, GJ, Talan, DA & Abrahamian, FM 2008, Antimicrobial prophylaxis for wounds and procedures in the emergency department. Infectious Disease Clinics of North America, 22: 117-143.
Morgan, M 2005, Hospital management of animal and human bites. Journal of hospital infection 61, 1-10.
Morgan, M, Palmer, J 2007 Dog bites. BMJ, 334: 413-417.
Peel, M, Hornidge, K, Luppino, M, Stacpoole, A, Weaver, R 1991, Actinobacillus spp. and related bacteria in infected wounds of humans bitten by horses and sheep. Journal of Clinical Microbiology, 29: 2535-2538.
Radjou, A, Hanifah, M & Govindaraj, V 2012, Tetanus following dog bite. Indian Journal of Community Medicine 37: 200.
Rahman, R, Faiz, MA, Selim, S, Rahman, B, Basher, A, Jones, A, d'Este, C, Hossain, M, Islam, Z, Ahmed, H 2010 Annual incidence of snake bite in rural Bangladesh. PLoS Neglected Tropical Diseases, 4: e860.
Singh, A & Jain, R  2016, Staphylococcus xylosus Meningitis Following Dog-bite. Indian Pediatrics, 53: 931-931.
Smith, DK, Grohskopf, LA, Black, RJ, Auerbach, JD, Veronese, F, Struble, KA, Cheever, L, Johnson, M, Paxton, LA & Onorato, IM 2005, Antiretroviral post-exposure prophylaxis after sexual, injection-drug use, or other nonoccupational exposure to HIV in the United States: Recommendations from the US Department of Health and Human Services. Morbidity and Mortality Weekly Report: Recommendations and Reports, 54: 1-20.
Sudarshan, M, Mahendra, B, Madhusudana, S, Narayana, DA, Rahman, A, Rao, N, X-Meslin, F, Lobo, D & Ravikumar, K 2006, An epidemiological study of animal bites in India: results of a WHO sponsored national multi-centric rabies survey. Journal of Communicable Diseases 38, 32.
Taplitz, RA 2004, Managing bite wounds: Currently recommended antibiotics for treatment prophylaxis. Postgraduate medicine 116, 49-59.
Ward, MA 2013, Bite wound infections. Clinical Pediatric Emergency Medicine, 14: 88-94.
Warrell, DA 2010, Snake bite. The Lancet, 375: 77-88.
Weber, DJ, Rutala, WA, Kaplan, SL, Calderwood, SB, Edwards, MS and Baron, EL, 2016 Pasteurella infections.  2016. Pasteurellosis Status in Ethiopia: A Comprehensive Review. Journal of Tropical Diseases and Public Health, 8: 351-355.
Wilde, H, Lumlertdacha, B, Meslin, FX, Ghai, S, Hemachudha, T 2016 Worldwide rabies deaths prevention - A focus on the current inadequacies in postexposure prophylaxis of animal bite victims. Vaccine, 34: 187-189.