Effects of the silver nanoparticle synthesis from the leaves of the Capparis spinosa plant on the liver of mice infected with visceral leishmaniasis

Document Type : Research Paper


Department of Biology, College of Science, AL-Mustansiriyah University, Iraq


To know the effect of the Capparies silver nanoparticles (AgNPs) synthesis from the leaves of the Capparis spinosa plant on the liver enzymes GOT, GPT and the histology of the liver in infected mice with visceral leishmaniasis (VL), they were dosed with 0.1 mL day-1 and pentostam drug (0.01 mL day-1) for 21 days. The results showed that the silver nanoparticles of the Capparies spinosa, led to a significant decrease in liver enzymes, i.e., GOT and GPT after three weeks, compared to the positive control group. Also, it was noted that the liver tissue was less affected with a slight expansion of the hepatic sinusoids and a decrease in lymphocyte infiltration.


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