Using amniotic membrane for effective epithelialization of surgical wounds after cesarean section

Authors

1 Institute of Genetics and Physiology, Committee of Science Ministry of Science and Higher Education of the Republic of Kazakhstan, Almaty, Kazakhstan

2 Non-Profit Joint Stock Company “S.D. Asfendiyarov Kazakh National Medical University,” Almaty, Kazakhstan

3 LLP “Scientific and Production Technical Center ‘Zhalyn’,” Almaty, Kazakhstan

10.22124/cjes.2025.9377

Abstract

The purpose of this clinical trial, conducted on 80 patients between March and December 2024 referred to Almaty Teaching Hospital, was to evaluate the effect of amniotic membrane on wound healing after cesarean section. Patients were randomly divided into two intervention groups-recipients of amniotic membrane-and control-recipients of standard dressing. The results showed that the time to complete epithelialization in the intervention group was an average of 10.2 days, being significantly lower than 15.8 days in the control group, with a p-value of less than 0.001. Moreover, the incidence of wound infection was only 2.5% in the intervention group, while this rate reached 17.5% in the control group, with a p-value of 0.025. Based on the VAS scale, pain intensity in the intervention group was significantly lower than in the control group during all early postoperative days. Furthermore, assessment of patient satisfaction and scar appearance based on the POSAS questionnaire was also more favorable in the intervention group. Finally, the length of hospitalization was shorter in this group. This study concludes that the application of amniotic membrane can be integrated as an effective complementary method in post-cesarean care protocols by accelerating recovery, reducing complications, and increasing patient satisfaction.
 

Keywords

References

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Caspian Journal of Environmental Sciences
Volume 23, Issue 5
Special issue: Biological Researches and Envireonment, Guest Editor: Prof. Hamed Mousavi-Sabet, University of Guilan, Iran
December 2025
Pages 1379-1386

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