Physiological and histological alterations in laboratory rabbits infected with Necator americanus (Nematoda: Ancylostomatidae)

Document Type : Research Paper

Authors

1 Department of Pathological Analysis, Faculty of Applied Science, University of Samarra, Iraq

2 Department of Biology, Faculty of Education, University of Samarra, Iraq

3 Department of Biology, Faculty of Science, University of Sfax, Tunis

10.22124/cjes.2024.7601

Abstract

The present study was conducted for the period from April to October 2022 in University of Samarra laboratories, Iraq. The study included 20 male laboratory rabbits, whose weight ranged from 1.4 to 1.5 kg, ten of them were as a control group and the other ten were infected with N. americanus parasite. Some biochemical tests were carried out such as lipid profile (HDL, Cholesterol, and Triglycerides) and liver enzymes (GOT and GPT), as well as tissue sections of the liver, lung and small intestine to see the alterations due to infection. The present results showed significant differences for total cholesterol between control and infected groups (88.40 and 71.80 mg dL-1, respectively). In the case of triglycerides, non-significant variances were recorded between control and infected groups (68.80 and 69.80 mg dL-1, respectively), whereas in the case of HDL, the present results showed significant differences between control and infected groups (27.40 and 22.60 mg dL-1, respectively). The current results showed significant increase in concentration of GOT of infected group compared to control group (27.20 and 15.60 mg dL-1, respectively). As for GPT, non-significant variances were recorded between infected and control groups (17.80 and 14.60 mg dL-1, respectively), while for Iron, significant differences occured between infected and control groups (74.00 and 101.40 mg dL-1 respectively). The histological study showed the presence of histological alterations in the members of infected group.

Keywords

References

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Caspian Journal of Environmental Sciences

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Available Online from 24 February 2024

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