Physiological and histological alterations in laboratory rabbits infected with Necator americanus (Nematoda : Ancylostomatidae)

Articles in Press

Document Type : Research Paper

Authors

1 Department of Pathological Analysis, Faculty of Applied Science, University of Samarra, Iraq

2 Department of Biology, Faculty of Education, University of Samarra, Iraq

3 Department of Biology, Faculty of Science, University of Sfax, Tunis

10.22124/cjes.2024.7505

Abstract

The present study was conducted for the period from April to October 2022 in University of Samarra laboratories. The study included 20 male laboratory rabbits, whose weight ranged from (1.4-1.5) Kg, ten of them were as a control group and the other ten were infected with N. americanus parasite. Some biochemical tests such as lipid profile (HDL, Cholesterol, and Triglycerides) and liver enzymes (GOT and GPT), as well as tissue sections of the liver, lung and small intestine to see the changes that occur due to infection. The present results showed significant differences for total cholesterol between control and infected groups (88.40 and 71.80) mg/dl, respectively, as for triglycerides, non-significant variances were recorded between control and infected groups (68.80 and 69.80) mg/dL, respectively, whereas for HDL the present results showed significant differences between control and infected groups (27.40 and 22.60) mg/dL, respectively. The current results showed significant increase in concentration of GOT of infected group compared with control group (27.20 and 15.60) mg/dL, respectively, as for GPT, non-significant variances were recorded between infected and control groups (17.80 and 14.60) mg/dL, respectively, while for Iron, significant differences occure between infected and control groups (74.00 and 101.40) mg/dL, respectively. The histological study showed the presence of histological changes in the members infected group that were studied.

Keywords

Caspian Journal of Environmental Sciences

Articles in Press, Corrected Proof
Available Online from 04 February 2024

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