Effects of sophoroflavonoside and narcissin flavonoids on the amount of malondialdehyde, a product of lipid peroxidation, and the activity of the enzyme cytochrome c oxidase in rat liver mitochondria poisoned with indoxacarb pesticide


1 Andijan State University, Andijan City

2 Tashkent State Pedagogical University Named after Nizomi, Tashkent City

3 M. Ulugbek National University of Uzbekistan, Tashkent City

4 Tashkent State Agrarian University, Tashkent City, Republic of Uzbekistan



In this study, the effects of soforaflavonolonoside and narcissin flavonoids on the amount of malondialdehyde, a product of peroxidation of lipids in the liver mitochondria of rats poisoned with indoxacarb pesticide, and on the activity of the enzyme cytochrome-s-oxidase were studied depending on the dynamics of 10, 20, 30 and 40 days. The experimental group was injected with indoxacarb pesticide at a dose of 1/10 LD50 through a special probe. After administration of indoxacarb pesticide, animals were administered orally with soforaflavonolonoside and narcissin flavonoid at a dose of 10 mg kg-1 once a day for 10 days.


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