Antioxidant effects of methanolic extracts of Anthemis Susiana Nabelek, Alyssum campestre, and Gundelia tournefortii

Document Type : Research Paper

Authors

1 Social Determinants of Health Research Centre, Shahid Rahimi Hospital, School of Nursing & Midwifery, Lorestan University of Medical Sciences, Khorramabad, Iran

2 Shahrekord Branch, Islamic Azad University, Shahrekord, Iran

3 Department of Food Science and Technology, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Science and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran

4 Department of Food Hygiene, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran

10.22124/cjes.2023.6714

Abstract

One of the prominent effects of free radical activity in the body is damage to biological and vital molecules such as nucleic acids, proteins and lipoprotes. So, free radicals, especially reactive oxygen species, play an important role in medical issues. Using compounds that neutralize free radicals, i.e. antioxidants, is a suitable choice to minimize the damage caused by their production. Herbs are recognized as rich sources of antioxidants and consumption of these plants can be effective for human health. The present study was conducted to evaluate the antioxidant property of native medicinal plants including Babouneh shoshi, Anthemis Susiana Nabelek, Ghodoumeh dokhtari, Alyssum campestre, and Kangar, Gundelia tournefortii in Ilam Province, Iran. Total antioxidant capacity was measured using at 570 nm with the enzyme-linked immunosorbent assay (ELISA). The results showed that the total antioxidant capacities of Babouneh shoshi, Ghodoumeh dokhtari, and Kangar are 4.29, 1.01 and 1.25 mmol Fe2+ L-1, respectively. Generally, there are several natural antioxidant compounds in Iranian medicinal herbs which made them as reliable sources for therapeutic purposes. The essential oils of these plants are the source of herbal secondary metabolites with antioxidant and antimicrobial effects that are recommended for their use in the food, pharmaceutical, and health industries.
 

Keywords


Akhtarian, N, Khosraviar, S & Golmakani, A 2015, Study of phenolic compounds of dichloromethane, methanolic and ethyl acetate extracts of Qadomeh plant, 23rd National Congress of Food Science and Technology of Iran, Quchan, , 1https: //civilica.com/doc/563798.
AL-Qadhi, NA, Ibrahim, EK, Khalaf, RN, Abass, KS, Abbas, QS 2020, Antioxidant effect of Gundelia tournefortii Extract on Some Physiological, Biochemical and Histopathological Changes in Male Rats. The Journal of Research on the Lepidoptera, 51: 479-495
Altememy, D, Bahmani, M, Hussam, F, Karim, YS, Kadhim, MM, Khawaja, WK, Hameed, NM, Alwan, NH, Darvishi, M 2022, Determination of total antioxidant content of methanolic extracts of Cynara scolymus, Echinacea purpurea and Portulaca oleracea. Advancements in Life Sciences, 9: 395-400.
Amiri, MM, Fayyadh, SH, Parra, RM, Al-Khafaji, AH, Abosaooda, M, Darvishi, M & Emadichashmi, S 2023, Role of selective cyclooxygenase-2 inhibitors in renal colic pain reduction and improvement: A systematic review of clinical trials. Advancements in Life Sciences, 9: 446-452.
Annegowda, H, Mordi M, Ramanathan S, Hamdan M, Mansor S 2012, Effect of extraction techniques on phenolic content, antioxidant and antimicrobial activity of Bauhinia purpurea: HPTLC determination of antioxidants. Food Analytical Methods, 5: 226-233.
Arumugam, P, Ramamurthy, P & Ramesh, A 2010, Antioxidant and cytotoxic activities of lipophilic and hydrophilic fractions of Mentha spicata L.(Lamiaceae). International Journal of Food Properties, 13: 23-31.
Bahrami, Kia, Saifullah, Azizi Moradi, F 2015, Antioxidant and chelating activity of ethanolic extract of Gundelia tournefortii Lorestan. 1st Scientific Conference on Biology and Horticulture in Iran, Tehran, (205), https: // civilica .com / doc / 393482.
Bai, N, He, K, Roller, M, Lai, C-S, Shao, X, Pan, M-H, et al. 2010, Flavonoids and phenolic compounds from Rosmarinus officinalis. Journal of Agricultural and Food Chemistry, 58:5363-5367.
Ceylan, S, Cetin, S, Camadan, Y, Saral, O, Ozsen, O, Tutus, A 2019, Antibacterial and antioxidant activities of traditional medicinal plants from the Erzurum region of Turkey. Irish Journal of Medical Science, 188: 1303-1309.
Chon, SU, Kim, YM, Park, YJ, Heo, BG, Park, YS & Gorinstein, S 2009, Antioxidant and antiproliferative effects of methanol extracts from raw and fermented parts of mulberry plant (Morus alba L.). European Food Research and Technology, 230:231-237.
Darvishi, M, Tosan, F, Nakhaei, P, Manjili, DA, Kharkouei, SA, Alizadeh A, Ilkhani, S, Khalafi, F, Zadeh, FA, Shafagh, SG 2022, Recent progress in cancer immunotherapy: Overview of current status and challenges. Pathology-Research and Practice, 24:154241.
Eftakhari, Z, Patra, I, Hamza, TA, Adhab, AH, Hachim, S, Abulkassim, R, Hameed, NM & Naghdi, N 2022, Evaluation of the total antioxidant capacity of bitter and sweet varieties of Ferula assa-foetida and Bunium persicum. Advancements in Life Sciences, 9: 363-367.
El-Ghorab A, El-Massry KF & Shibamoto T 2007, Chemical composition of the volatile extract and antioxidant activities of the volatile and nonvolatile extracts of Egyptian corn silk (Zea mays L.). Journal of Agricultural and Food Chemistry, 55: 9124-9127.
Ertuğ, F 2000, An ethnobotanical study in central Anatolia (Turkey). Economic Botany, 54: 155-182.
Falahi, E, Delshadian, Z, Ahmadvand, H & Shokri Jokar, S 2019, Head space volatile constituents and antioxidant properties of five traditional Iranian wild edible plants grown in west of Iran. AIMS Agriculture and Food, 7: 5.
Fazeli-Nasab, B, Rahnama & Mazarei A 2017, Correlation between antioxidant activity and antibacterial activity of nine medicinal plant extracts. Journal of Mazandaran University of Medical Sciences, 27: 63-78.
Hasanvand, A, Ebrahimi, Y, Mohamadi, A & Nazari, A 2019, Zingiber officinale Roscoe reduces chest pain on patients undergoing coronary angioplasty: a clinical trial. Journal of Herbmed Pharmacology, 8: 47-50.
Hayouni, EA, Abedrabba, M, Bouix, M & Hamdi M 2007, The effects of solvents and extraction method on the phenolic contents and biological activities in vitro of Tunisian Quercus coccifera L. and Juniperus phoenicea L. fruit extracts. Food Chemistry, 105: 1126-1134.
Ibrahim, GI, Jalal, AF & Ibrahim M 2013, Evaluation of antioxidant activity, phenolic, flavonoid and ascorbic acid contents of three edible plants from Erbil/Kurdistan. Tikrit Journal of Pure Science, 18: 46-51.
Jamshidzadeh, A, Fereidooni, F, Salehi, Z, Niknahad, H 2005, Hepatoprotective activity of Gundelia tourenfortii. Journal of Ethnopharmacology, 101: 233-237.
Javaid, A, Chaudhury, FA, Khan, IH, Ferdosi, MF 2023, Potential health-related phytoconstituents in leaves of Chenopodium quinoa. Advancements in Life Sciences, 21;9(4):574-88.
Karis, PO, Eldenäs P & Källersjö, M 2001, New evidence for the systematic position of Gundelia L. with notes on delimitation of Arctoteae (Asteraceae). Taxon, 50(1):105-14.
Khademian Amiri, S, A. Aghajanzadeh, T, Afari, NJ & Mahmoudi, M 2022, Antioxidative compounds, enzymes activity and nutrient elements in Stachys byzantina are altered by climate conditions not by soil parameters. Caspian Journal of Environmental Sciences, 20: 1099-1115. DOI: 10.22124/cjes.2022.6091
Manouchehri A, Shakib P, Biglaryan F, Nazer M & Darvishi, M 2021, The most important medicinal plants affecting bee stings: A systematic review study. Uludağ Arıcılık Dergisi, 21: 91-103.
Manouchehri, A, Marznaki, ZH, Atim, LM & Kaggwa, MM 2022, The relationship between causes of suicidal attempts in Iran and individual and social variables: A retrospective study. BMC Psychiatry, 22: 1.
Shahsavari, S, Mandal, S, Ganguly, P & Mandal SK 2022, Evaluation of the total antioxidant effect of methanolic extract of Nasturtium Officinale. Journal of Biochemicals and Phytomedicine. 1: 21-25, DOI: 10.34172/jbp.2022.6.
Shahsavari, S, Sarkar, S, Sen, DJ & Mandal, SK 2022, Determination of total antioxidant activity of methanolic extract of Falcaria vulgaris. Journal of Biochemicals and Phytomedicine, 1: 8-12, DOI: 10.34172/jbp.2022.3.
Usunobun, U & Imoru, O 2022, Evaluation of hepatoprotective potential of Chromolaena odorata (L.) R.M. King & H. Rob. against methotrexate-induced hepatic toxicity in rats. Plant Biotechnology Persa, 4: 12-21
Valko M, Rhodes C, Moncol J, Izakovic M & Mazur M 20006, Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chemico-Biological Interactions, 160: 1-40.
Wong F-C, Xiao J, Wang S, Ee K-Y & Chai T-T 2020, Advances on the antioxidant peptides from edible plant sources. Trends in Food Science & Technology, 99:44-57.
Zarabi, S, Ahmadi, S & Rostami, R 2017, Anticancer activity evaluation of methanolic extract of Allium jesdianum and Nectaroscordeum coelzi against HeLa and K562 cell lines. Yafte, 19: 7.
Zarban Malekaneh, M, Hassanpour, M, Najjari & M 2004, Evaluation of antioxidant properties of 28 Iranian medicinal plants. Scientific Journal of Birjand University of Medical Sciences, 11: 9-15.