Antibacterial activity, anti-adherence and anti-biofilm activities of plants extracts against Aggregatibacter actinomycetemcomitans: An in vitro study in Hilla City, Iraq

Document Type : Research Paper

Authors

1 Department of Anesthesia Techniques, Al- Mustaqbal University College, Babylon Province Iraq

2 Department of Basic and Medical Science, College of Nursing, Babylon University, Babylon Province, Iraq

3 Department of Clinical Laboratory Sciences, College of Pharmacy, University of Babylon, Babylon Province, Iraq

4 Microbiology Department, College of veterinary medicine, Green Al-Qasim University, Babylon Province, Iraq

5 Virology Department, Faculty of Biology and Ecology, Yanka Kupala State University of Grodno, Grodno, Belarus

10.22124/cjes.2022.5578

Abstract

The current study was designed to establish the antibacterial efficacy of various extracts from medicinal plants. The inhibition effects of six plants including Viscus album, Apium graveolens, Melissa officinalis, Plantago ovata, Senna acutifolia, and Vitis vinifera were examined against Aggregatibacter actinomycetemcomitans, which obtained from dental caries patient. The output showed that the tested bacterial isolates were greatly sensitive to M.  officinalis and S. acutifolia and their maximum inhibition zones were 35 mm and 33 mm respectively. The tested bacterial isolates were greatly sensitive to M.  officinalis and S. acutifolia in comparison with the antibiotic. According to the well-diffusion test results, the crude aqueous extracts from the plants showed varying degrees of inhibition of bacterial growth. Moreover, these medicinal plant extracts were a promising group of natural product sources that can be examined to continue developing products through the use of oral medicines and health care.

Keywords


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