University of Guilan Caspian Journal of Environmental Sciences 1735-3033 22 2 2024 04 01 Temporal and spatial dynamics of bovine spongiform encephalopathy prevalence in Akmola Province, Kazakhstan: Implications for disease management and control 431 442 7734 10.22124/cjes.2024.7734 EN Satia N. Lubis Department of Regional Planning, Postgraduate school, Universitas Sumatera Utara, Indonesia Bakhtiyor Menglikulov Tashkent State University of Economics, Uzbekistan Rustem Shichiyakh Department of Management, Kuban State Agrarian University named after I.T. Trubilin, Krasnodar, Russia Qodirov Farrux Department of Informatics and its Teaching Methodology" of Shakhrisabz State Pedagogical Institute, Uzbekistan Bobojonov O. Khakimboy Ugli Department of Fruits and Vegetables at the Urganch State University, Uzbekistan Tadjibaeva M. Karimbaevna Department of zoology, Human Morphophysiology and Nutrition, Nukus State Pedagogical Institute named after Ajiniyaz, Uzbekistan Kholmirzaev Ulugbek Namangan Engineering-Construction Institute, Uzbekistan Suyunova Z. Bakhtiyarovna Department of Genetics, Selection, Breeding and Reproduction of Animals, Samarkand State University of Veterinary Medicine, Livestock and Biotechnologies (SSUV), Uzbekistan Jurabekova Khabiba Andijan Machine-Building Institute, Andijan, Uzbekistan; Western Caspian University, Baku, Azerbaijan I.B. Sapaev Tashkent Institute of Irrigation and Agricultural Mechanization Engineers National Research University, Tashkent, Uzbekistan, University of Tashkent for Applied Sciences, Str. Gavhar 1, Tashkent 100149, Uzbekistan Saidov Jasur Department of Applied Mathematics and Information Technologies of Gulistan State University, Uzbekistan Journal Article 2024 05 01 Bovine Spongiform Encephalopathy (BSE), commonly known as "mad cow disease," is a fatal neurological disorder in cattle attributed to abnormal brain protein aggregation. This disease presents multifaceted challenges, encompassing public health concerns due to potential transmission to humans, challenging disease control in cattle, and economic impacts on the livestock industry and global trade. Understanding the complex science of prion diseases like BSE is essential for managing and preventing its spread. We conducted a comprehensive investigation into BSE prevalence over the past decade in Akmola Province<strong> </strong>to analyse its temporal and spatial dynamics. The study explores the progression of BSE from its introduction into the cattle population to the establishment of enzootic equilibrium, highlighting the impact of control measures and key determinants influencing prevalence growth. Our findings offer valuable insights into the spatiotemporal patterns of BSE prevalence and its implications for disease management. https://cjes.guilan.ac.ir/article_7734_40564254af34c4db67afa3d51cec3f6d.pdf